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1

Subependymal giant cell astrocytoma-like astrocytoma: a neoplasm with a distinct phenotype and frequent neurofibromatosis type-1-association

Palsgrove, Doreen N., Brosnan-Cashman, Jacqueline A., Giannini, Caterina, Raghunathan, Aditya, Jentoft, Mark, Bettegowda, Chetan, Gokden, Murat, Lin, Doris, Yuan, Ming, Lin, Ming-Tseh, Heaphy, Christo

Journal:

Modern Pathology

Year:

2018

Language:

english

File:

PDF, 4.34 MB

english, 2018

2

Alternative lengthening of telomeres, ATRX loss and h3-k27m mutations in histologically defined pilocytic astrocytoma with anaplasia

Rodriguez, Fausto J., Brosnan-Cashman, Jacqueline A., Allen, Sariah J., Vizcaino, M. Adelita, Giannini, Caterina, Camelo-Piragua, Sandra, Webb, Milad, Matsushita, Marcus, Wadhwani, Nitin, Tabbarah, Ab

Journal:

Brain Pathology

Year:

2018

Language:

english

File:

PDF, 2.46 MB

english, 2018

3

HGG-08. ATRX LOSS IN PEDIATRIC GBM RESULTS IN EPIGENETIC DYSREGULATION OF G2/M CHECKPOINT MAINTENANCE AND SENSITIVITY TO ATM INHIBITION

Mullan, Brendan, Qin, Tingting, Siada, Ruby, Danussi, Carla, Brosnan-Cashman, Jacqueline, Pratt, Drew, Garcia, Taylor, Yadav, Viveka Nand, Zhao, Xinyi, Morgan, Meredith, Venneti, Sriram, Meeker, Alan,

Journal:

Year:

2019

Language:

english

File:

PDF, 90 KB

english, 2019

4

ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma

Koschmann, C., Calinescu, A.-A., Nunez, F. J., Mackay, A., Fazal-Salom, J., Thomas, D., Mendez, F., Kamran, N., Dzaman, M., Mulpuri, L., Krasinkiewicz, J., Doherty, R., Lemons, R., Brosnan-Cashman, J.

Journal:

Science Translational Medicine

Year:

2016

Language:

english

File:

PDF, 2.22 MB

english, 2016

5

Alternative lengthening of telomeres in primary pancreatic neuroendocrine neoplasms is associated with aggressive clinical behavior and poor survival

Kim, J. Y., Brosnan-Cashman, J. A., An, S., Kim, S. J., Song, K. B., Kim, M.-S., Kim, M.-J., Hwang, D. W., Meeker, A. K., Yu, E., Kim, S. C., Hruban, R. H., Heaphy, C. M., Hong, S.-M.

Journal:

Clinical Cancer Research

Year:

2016

Language:

english

File:

PDF, 13.30 MB

english, 2016

6

GENE-17. ATRX LOSS IN GLIOMA RESULTS IN EPIGENETIC DYSREGULATION OF THE G2/M CHECKPOINT AND SENSITIVITY TO ATM INHIBITION

Mullan, Brendan, Qin, Tingting, Siada, Ruby, Ravindran, Ramya, Garcia, Taylor, Muruganand, Ashwath, Harris, Micah, Danussi, Carla, Brosnan-Cashman, Jacqueline, Pratt, Drew, Zhao, Xinyi, Rehemtulla, Al

Journal:

Year:

2019

Language:

english

File:

PDF, 93 KB

english, 2019

7

HGG-08. ATRX LOSS IN PEDIATRIC GBM RESULTS IN EPIGENETIC DYSREGULATION OF G2/M CHECKPOINT MAINTENANCE AND SENSITIVITY TO ATM INHIBITION

Mullan, Brendan, Qin, Tingting, Siada, Ruby, Danussi, Carla, Brosnan-Cashman, Jacqueline, Pratt, Drew, Garcia, Taylor, Yadav, Viveka Nand, Zhao, Xinyi, Morgan, Meredith, Venneti, Sriram, Meeker, Alan,

Journal:

Year:

2019

File:

PDF, 90 KB

2019

8

Functional loss of ATRX and TERC activates Alternative Lengthening of Telomeres (ALT) in LAPC4 prostate cancer cells

Graham, Mindy K, Kim, Jiyoung, Da, Joseph, Brosnan-Cashman, Jacqueline A, Rizzo, Anthony, Baena Del Valle, Javier A., Chia, Lionel, Rubenstein, Michael, Davis, Christine, Zheng, Qizhi, Cope, Leslie, C

Journal:

Molecular Cancer Research

Year:

2019

Language:

english

File:

PDF, 1.64 MB

english, 2019

9

ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner

Brosnan-Cashman, Jacqueline A., Yuan, Ming, Graham, Mindy K., Rizzo, Anthony J., Myers, Kaylar M., Davis, Christine, Zhang, Rebecca, Esopi, David M., Raabe, Eric H., Eberhart, Charles G., Heaphy, Chri

Journal:

Year:

2018

Language:

english

File:

PDF, 16.35 MB

english, 2018

10

Pancreatic acinar cell carcinomas and mixed acinar-neuroendocrine carcinomas are more clinically aggressive than grade 1 pancreatic neuroendocrine tumours

Kim, Joo Young, Brosnan-Cashman, Jacqueline A., Kim, Jiyoon, An, Soyeon, Lee, Kyoung-Bun, Kim, Haeryoung, Park, Do Youn, Jang, Kee-Taek, Oh, Young-Ha, Hruban, Ralph H., Heaphy, Christopher M., Hong, S

Journal:

Year:

2020

Language:

english

File:

PDF, 5.66 MB

english, 2020

11

Pervasive promoter hypermethylation of silenced TERT alleles in human cancers

Esopi, David, Graham, Mindy Kim, Brosnan-Cashman, Jacqueline A., Meyers, Jennifer, Vaghasia, Ajay, Gupta, Anuj, Kumar, Balasubramanian, Haffner, Michael C., Heaphy, Christopher M., De Marzo, Angelo M.

Journal:

Cellular Oncology

Year:

2020

File:

PDF, 2.61 MB

2020

12

Telomere alterations in neurofibromatosis type 1-associated solid tumors

Rodriguez, Fausto J., Graham, Mindy K., Brosnan-Cashman, Jacqueline A., Barber, John R., Davis, Christine, Vizcaino, M. Adelita, Palsgrove, Doreen N., Giannini, Caterina, Pekmezci, Melike, Dahiya, Son

Journal:

Acta Neuropathologica Communications

Year:

2019

Language:

english

File:

PDF, 1.55 MB

english, 2019

13

The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma

Diplas, Bill H., He, Xujun, Brosnan-Cashman, Jacqueline A., Liu, Heng, Chen, Lee H., Wang, Zhaohui, Moure, Casey J., Killela, Patrick J., Loriaux, Daniel B., Lipp, Eric S., Greer, Paula K., Yang, Rui,

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.95 MB

english, 2018

14

GENE-01. THE GENOMIC LANDSCAPE OF TRIPLE-NEGATIVE GLIOBLASTOMA

Diplas, Bill H, Waitkus, Matthew S, He, Xujun, Brosnan-Cashman, Jackie, Liu, Heng, Chen, Lee, Wang, Zhaohui, Moure, Casey, Killela, Patrick, Lipp, Eric S, Rodriguez, Fausto J, Jiao, Yuchen, McClendon,

Journal:

Year:

2018

Language:

english

File:

PDF, 123 KB

english, 2018

15

Mutated Chromatin Regulatory Factors as Tumor Drivers in Cancer

Koschmann, Carl, Nunez, Felipe J., Mendez, Flor, Brosnan-Cashman, Jacqueline A., Meeker, Alan K., Lowenstein, Pedro R., Castro, Maria G.

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 302 KB

english, 2017

16

GENE-42. THE GENOMIC LANDSCAPE OF TRIPLE-NEGATIVE GLIOBLASTOMA

Diplas, Bill, Waitkus, Matthew, He, Xujun, Brosnan-Cashman, Jackie, Liu, Heng, Chen, Lee, Wang, Zhaohui, Moure, Casey, Killela, Patrick, Lipp, Eric, Rodriguez, Fausto, Jiao, Yuchen, McLendon, Roger, B

Journal:

Year:

2018

Language:

english

File:

PDF, 88 KB

english, 2018

17

GENE-17. ATRX LOSS IN GLIOMA RESULTS IN EPIGENETIC DYSREGULATION OF THE G2/M CHECKPOINT AND SENSITIVITY TO ATM INHIBITION

Mullan, Brendan, Qin, Tingting, Siada, Ruby, Ravindran, Ramya, Garcia, Taylor, Muruganand, Ashwath, Harris, Micah, Danussi, Carla, Brosnan-Cashman, Jacqueline, Pratt, Drew, Zhao, Xinyi, Rehemtulla, Al

Journal:

Year:

2019

File:

PDF, 93 KB

2019

18

Genetic alterations associated with ALTered telomeres

Brosnan-Cashman, Jacqueline A., Graham, Mindy K., Heaphy, Christopher M.

Journal:

Year:

2018

Language:

english

File:

PDF, 707 KB

english, 2018

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